Eastern Journal of Psychiatry

Register      Login

VOLUME 24 , ISSUE 1 ( January-June, 2024 ) > List of Articles

Original Article

The Trend of Utilization of Opioid Substitution Therapy Services in the Prepandemic Era in a Tertiary Medical College in India

Dr Ranjan Bhattacharyya, Supriya K Mondal, Soumen Mondal, Koushik Banik, Nazmul Khan

Keywords : Buprenorphine substitution, Cumulative service, Opioid substitution therapy, Regular attendance, Sexually transmitted infection clinic, Tertiary care

Citation Information : Bhattacharyya DR, Mondal SK, Mondal S, Banik K, Khan N. The Trend of Utilization of Opioid Substitution Therapy Services in the Prepandemic Era in a Tertiary Medical College in India. 2024; 24 (1):16-21.

DOI: 10.5005/jp-journals-11001-0076

License: CC BY-NC 4.0

Published Online: 08-06-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Introduction: Human immunodeficiency virus (HIV) prevention among intravenous drug user (IDU) is the ultimate goal of National AIDS Control Organization (NACO). The government hospitals across India are expanding with opioid substitution therapy (OST) services. Aims and objectives: The primary aim was to find out the pattern of hopsacking behavior in a newly functional OST clinic in a government setup in India. As the prevalence of HIV infection is on rise, requirement of opening OST clinic are also emerging. Materials and methods: The datasheet has been made in accordance with guidelines, and the descriptive and analytical statistics study has been carried out in a tertiary medical college of a government setup in India. The new patients enrolled, total clients registered, active client load, and total client load have increased at the beginning and end of the study period. The data were analyzed using IBM Statistical Package for the Social Sciences (SPSS) version 20.0. Results: New clients enrolled during the study period are n = 62. From inception, total clients raised to 202. Very regular, regular, and irregular clients were n = 27, 10, and 72 changed to n = 56, 22, and 13, respectively from beginning to end of the study which is statistically not significant χ2 = 0.0792, p = 0.961. Total number of client vs active clients during beginning and end of the study shows significance, χ2 = 25.3311, p < 0.001. The relationship between new clients, total clients, treatment completed, clients with other outcome and active client shows significance in 2 × 5 contingency table, χ2 = 99.3704, p < 0. 001.The relationship between sexually transmitted infection (STI) referral, HIV tested, and condoms dispensed has shown significance with χ2 = 6.071, p < 0.048. Conclusion: Opioid substitution therapy is an effective therapeutic option to manage IV drug users. The screening with stringent criteria is essential before client selection.

PDF Share
  1. Stöver H, Jamin D, Michels II, et al. Opioid substitution therapy for people living in German prisons-inequality compared with civic sector. Harm Reduct J 2019;16(1):72. DOI: 10.1186/s12954-019-0340-4
  2. Bart G. Maintenance medication for opiate addiction: the foundation of recovery. J Addict Dis 2012;31(3):207–225. DOI: 10.1080/10550887.2012.694598
  3. Blum K, Baron D. Opioid substitution therapy: achieving harm reduction while searching for a prophylactic solution. Curr Pharm Biotechnol 2019;20(3):180–182. DOI: 10.2174/138920102003190422150527
  4. Metzger DS, Woody GE, McLellan AT, et al. Human immunodeficiency virus seroconversion among intravenous drug users in- and out-of-treatment: an 18-month prospective follow-up. J Acquir Immune Defic Syndr 1993;6(9):1049–1056. DOI: 10.2188/jea.9.114
  5. Hou JY, Cao XB. An overview on the opioid substitution therapy service model. Zhonghua Liu Xing Bing Xue Za Zhi 2018;39(12):1655–1659. DOI: 10.3760/cma.j.issn.0254-6450.2018.12.022
  6. Sanger N, Bhatt M, Zielinski L, et al. Treatment outcomes in patients with opioid use disorder initiated by prescription: a systematic review protocol. Syst Rev 2018;7(1):16. DOI: 10.1186/s13643-018-0682-0
  7. Kourounis G, Richards BD, Kyprianou E, et al. Opioid substitution therapy: lowering the treatment thresholds. Drug Alcohol Depend 2016;161:1–8. DOI: 10.1016/j.drugalcdep.2015.12.021
  8. IBM Corp. Released 2011. IBM SPSS Statistics for Windows, Version 20.0. Armonk, New York: IBM Corp.
  9. Yadav R, Taylor D, Taylor G, et al. Community pharmacists’ role in preventing opioid substitution therapy-related deaths: a qualitative investigation into current UK practice. Int J Clin Pharm 2019;41(2):470–477. DOI: 10.1007/s11096-019-00790-x
  10. Dorabjee J, Samson L. Self and community based opioid substitution among opioid dependent populations in the Indian sub-continent. Int J Drug Policy 1998;9:411–416. DOI: 10.1016/S0955-3959(98)00057-7
  11. Kumar MS, Natale RD, Langkham B, et al. Opioid substitution treatment with sublingual buprenorphine in Manipur and Nagaland in Northeast India: what has been established needs to be continued and expanded. Harm Reduct J 2009;6:4. DOI: 10.1186/1477-7517-6-4
  12. Armstrong G, Kermode M, Sharma C, et al. Opioid substitution therapy in Manipur and Nagaland, north-east India: operational research in action. Harm Reduct J 2010;7:29. DOI: 10.1186/1477-7517-7-29
  13. Dhawan A, Chopra A. Does buprenorphine maintenance improve the quality of life of opioid users? Indian J Med Res 2013;137(1):130–135. PMID: 23481062.
  14. Rao R, Ambekar A, Yadav S, et al. Slow-release oral morphine as a maintenance agent in opioid dependence syndrome: an exploratory study from India. J Subst Use 2012;17:294–300. DOI: 10.3109/14659891.2011.583310
  15. Gale-Grant O, Bailey J, Burke O, et al. Use of prescribed psychotropic medications in an opioid substitution therapy cohort. J Dual Diagn 2019;15(4):254–259. DOI: 10.1080/15504263.2019.1662150
  16. Salsitz E, Wiegand T. Pharmacotherapy of opioid addiction: “putting a real face on a false demon.” J Med Toxicol 2016;12(1):58–63. DOI: 10.1007/s13181-015-0517-5
  17. von Hippel C, Henry JD, Terrett G, et al. Stereotype threat and social function in opioid substitution therapy patients. Br J Clin Psychol 2017;56(2):160–171. DOI: 10.1111/bjc.12128
  18. Kermode M, Crofts N, Kumar MS, et al. Opioid substitution therapy in resource-poor settings. Bull World Health Organ 2011;89(4):243. DOI: 10.2471/BLT.11.086850
  19. Scheibe A, Marks M, Shelly S, et al. Developing an advocacy agenda for increasing access to opioid substitution therapy as part of comprehensive services for people who use drugs in South Africa. S Afr Med J 2018;108(10):800–802. DOI: 10.7196/SAMJ.2018.v108i10.13397
  20. Parsons D, Burrows D, Bolotbaeva A. Advocating for opioid substitution therapy in Central Asia: much still to be done. Int J Drug Policy 2014;25(6):1174–1177. DOI: 10.1016/j.drugpo.2014.01.004
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.