Eastern Journal of Psychiatry

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VOLUME 16 , ISSUE 1-2 ( February-August, 2013 ) > List of Articles


Anti Psychotic Induced Hyperprolactinaemia

Zainab Lokhandwala Dawoodi, Avinash De Sousa

Keywords : Antipsychotics, hyperprolactinemia, prolactin

Citation Information : Dawoodi ZL, De Sousa A. Anti Psychotic Induced Hyperprolactinaemia. 2013; 16 (1-2):6-11.

DOI: 10.5005/EJP-16-1--2-6

License: CC BY-NC 4.0

Published Online: 13-10-2021

Copyright Statement:  Copyright © 2013; The Author(s).


Hyperprolactinaemia has for decades been an inevitable and neglected side-effect of antipsychotic medication. The recent introduction of prolactin-sparing antipsychotic agents makes a re-examination of this problem timely. This article aims to review the literature on antipsychotic induced hyperprolactinaemia and its consequences. A literature search was made for key articles, supplemented by cross referencing. During antipsychotic treatment prolactin concentrations can rise to ten times normal levels or above and existing data indicate that a large number of female patients have amenorrhoea with or without galactorrhoea. Survey data, however, suggest that clinicians underestimate the prevalence of these conditions. Antipsychotic-induced hyperprolactinaemia should become a focus of interest in the drug treatment of psychiatric patients.

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