Eastern Journal of Psychiatry

Register      Login

VOLUME 24 , ISSUE 2 ( July-December, 2024 ) > List of Articles

REVIEW ARTICLE

A Review Article on Neurobiological and Psychotherapeutic Approach in Management of Borderline Personality Disorder

Jyotika

Keywords : Neurobiological, Psychotherapy, Symptomatology

Citation Information : Jyotika. A Review Article on Neurobiological and Psychotherapeutic Approach in Management of Borderline Personality Disorder. 2024; 24 (2):39-44.

DOI: 10.5005/jp-journals-11001-0080

License: CC BY-NC 4.0

Published Online: 16-11-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

PDF Share
  1. McCabe GA, Widiger TA. A comprehensive comparison of the ICD-11 and DSM-5 section III personality disorder models. Psychol Assess 2020;32(1):72–84. DOI: 10.1037/pas0000772
  2. Bozzatello P, Blua C, Marin G, et al. Group interpersonal psychotherapy (IPT-G) for borderline personality disorder: a randomized controlled study. J Psychiatr Res 2023;168:157–164. DOI: 10.1016/j.jpsychires.2023.10.049
  3. ICD-11
  4. DSM-5
  5. Gunderson JG, Zanarini MC, Choi-Kain LW, et al. Family study of borderline personality disorder and its sectors of psychopathology. Arch Gen Psychiatry 2011;68:753–762. DOI: 10.1001/archgenpsychiatry.2011.65
  6. Torgersen S, Lygren S, Oien PA, et al. A twin study of personality disorders. Compr Psychiatry 2000;41:416–425. DOI: 10.1053/comp.2000.16560
  7. Kendler KS, Aggen SH, Czajkowski N, et al. The structure of genetic and environmental risk factors for DSM-IV personality disorders: a multivariate twin study. Arch Gen Psychiatry 2008;65:1438–1446. DOI: 10.1001/archpsyc.65.12.1438
  8. Flasbeck V, Brüne M. Association between childhood maltreatment, psychopathology and DNA methylation of genes involved in stress regulation: evidence from a study in borderline personality disorder. PLoS One. 2021;16(3):e0248514. DOI: 10.1371/journal.pone.0248514
  9. Stanley B, Siever LJ. The interpersonal dimension of borderline personality disorder: toward a neuropeptide model. Am J Psychiatry 2010;167:24–39. DOI: 10.1176/appi.ajp.2009.09050744
  10. Rausch J, Gabel A, Nagy K, et al. Increased testosterone levels and cortisol awakening responses in patients with borderline personality disorder: gender and trait aggressiveness matter. Psychoneuroendocrinology 2015;55:116–127. DOI: 10.1016/j.psyneuen.2015.02.002
  11. Bertsch K, Schmidinger I, Neumann ID, et al. Reduced plasma oxytocin levels in female patients with borderline personality disorder. Horm Behav 2013;63:424–429. DOI: 10.1016/j.yhbeh.2012.11.013
  12. Herpertz SC, Bertsch K. A new perspective on the pathophysiology of borderline personality disorder: a model of the role of oxytocin. Am J Psychiatry 2015;172:840–851. DOI: 10.1176/appi.ajp.2015.15020216
  13. Siever LJ. Neurobiology of aggression and violence. Am J Psychiatry 2008;165:429–442. DOI: 10.1176/appi.ajp.2008.07111774
  14. Barratt ES, Stanford MS, Kent TA, et al. Neuropsychological and cognitive psychophysiological substrates of impulsive aggression. Biol Psychiatry 1997;41:1045–1061. DOI: 10.1016/s0006-3223(96)00175-8
  15. Silbersweig D, Clarkin JF, Goldstein M, et al. Failure of frontolimbic inhibitory function in the context of negative emotion in borderline personality disorder. Am J Psychiatry 2007;164:1832–1841. DOI: 10.1176/appi.ajp.2007.06010126
  16. Dyck M, Loughead J, Kellermann T, et al. Cognitive versus automatic mechanisms of mood induction differentially activate left and right amygdala. Neuroimage 2011;54:2503–2513. DOI: 10.1016/j.neuroimage.2010.10.013
  17. Hansenne M, Pitchot W, Pinto E, et al. 5-HT1A dysfunction in borderline personality disorder. Psychol Med 2002;32:935–941. DOI: 10.1017/s0033291702005445
  18. Soloff P, Nutche J, Goradia D, et al. Structural brain abnormalities in borderline personality disorder: a voxel-based morphometry study. Psychiatry Res 2008;164:223–236. DOI: 10.1016/j.pscychresns.2008.02.003
  19. Schulze L, Schmahl C, Niedtfeld I. Neural correlates of disturbed emotion processing in borderline personality disorder: a multimodal meta-analysis. Biol Psychiatry 2016;79:97–106. DOI: 10.1016/j.biopsych.2015.03.027
  20. Kimmel CL, Alhassoon OM, Wollman SC, et al. Age-related parieto-occipital and other gray matter changes in borderline personality disorder: a meta-analysis of cortical and subcortical structures. Psychiatry Res Neuroimaging 2016;251:15–25. DOI: 10.1016/j.pscychresns.2016.04.005
  21. Koenigsberg HW, Fan J, Ochsner KN, et al. Neural correlates of the use of psychological distancing to regulate responses to negative social cues: a study of patients with borderline personality disorder. Biol Psychiatry 2009;66:854–863. DOI: 10.1016/j.biopsych.2009.06.010
  22. Schmitt R, Winter D, Niedtfeld I, et al. Effects of psychotherapy on neuronal correlates of reappraisal in female patients with borderline personality disorder. Biol Psychiatry Cogn Neurosci Neuroimaging 2016;1:548–557. DOI: 10.1016/j.bpsc.2016.07.003
  23. Perez DL, Vago DR, Pan H, et al. Frontolimbic neural circuit changes in emotional processing and inhibitory control associated with clinical improvement following transference-focused psychotherapy in borderline personality disorder. Psychiatry Clin Neurosci 2016;70(1):51–61. DOI: 10.1111/pcn.12357
  24. Cao Y, Xie H, Sun H, et al. Common and distinct patterns of gray matter alterations in young adults with borderline personality disorder and major depressive disorder. Eur Arch Psychiatry Clin Neurosci 2022;272(8):1569–1582. DOI: 10.1007/s00406-022-01405-9
  25. McMain SF, Chapman AL, Kuo JR, et al. The effectiveness of 6 versus 12 months of dialectical behavior therapy for borderline personality disorder: a noninferiority randomized clinical trial. Psychother Psychosom 2022;91(6):382–397. DOI: 10.1159/000525102
  26. Bedics JD, Atkins DC, Comtois KA, et al. Treatment differences in the therapeutic relationship and introject during a 2-year randomized controlled trial of dialectical behavior therapy versus nonbehavioral psychotherapy experts for borderline personality disorder. J Consult Clin Psychol 2012;80(1):66–77. DOI: 10.1037/a0026113
  27. Neacsiu AD, Lungu A, Harned MS, et al. Impact of dialectical behavior therapy versus community treatment by experts on emotional experience, expression, and acceptance in borderline personality disorder. Behav Res Ther 2014;53:47–54. DOI: 10.1016/j.brat.2013.12.004
  28. Stepp SD, Epler AJ, Jahng S, et al. The effect of dialectical behavior therapy skills use on borderline personality disorder features. J Pers Disord 2008;22(6):549–563. DOI: 10.1521/pedi.2008.22.6.549
  29. Davidson K, Norrie J, Tyrer P, et al. The effectiveness of cognitive behavior therapy for borderline personality disorder: results from the borderline personality disorder study of cognitive therapy (BOSCOT) trial. J Pers Disord 2006;20(5):450–465. DOI: 10.1521/pedi.2006.20.5.450
  30. Juul S, Jakobsen JC, Hestbaek E, et al. Short-term versus long-term mentalization-based therapy for borderline personality disorder: a randomized clinical trial (MBT-RCT). Psychother Psychosom 2023;92(5):329–339. DOI: 10.1159/000534289
  31. Arntz A, Jacob GA, Lee CW, et al. Effectiveness of predominantly group schema therapy and combined individual and group schema therapy for borderline personality disorder: a randomized clinical trial. JAMA Psychiatry 2022;79(4):287–299. DOI: 10.1001/jamapsychiatry.2022.0010
  32. Klein JP, Hauer-von Mauschwitz A, Berger T, et al. Effectiveness and safety of the adjunctive use of an internet-based self-management intervention for borderline personality disorder in addition to care as usual: results from a randomised controlled trial. BMJ Open 2021;11(9):e047771. DOI: 10.1136/bmjopen-2020-047771
  33. Sosic-Vasic Z, Schaitz C, Mayer B, et al. Treating emotion dysregulation in patients with borderline personality disorder using imagery rescripting: a two-session randomized controlled trial. Behav Res Ther 2024;173:104454. DOI: 10.1016/j.brat.2023.104454
  34. Reyes-López J, Ricardo-Garcell J, Armas-Castañeda G, et al. Clinical improvement in patients with borderline personality disorder after treatment with repetitive transcranial magnetic stimulation: preliminary results. Braz J Psychiatry 2018;40(1):97–104. DOI: 10.1590/1516-4446-2016-2112
  35. Schulze L, Grove M, Tamm S, et al. Effects of transcranial direct current stimulation on the cognitive control of negative stimuli in borderline personality disorder. Sci Rep 2019;9(1):332. DOI: 10.1038/s41598-018-37315-x
  36. Zanarini MC, Conkey LC, Temes CM, et al. Randomized controlled trial of web-based psychoeducation for women with borderline personality disorder. J Clin Psychiatry 2018;79(3):16m11153. DOI: 10.4088/JCP.16m11153
  37. Zaehringer J, Ende G, Santangelo P, et al. Improved emotion regulation after neurofeedback: a single-arm trial in patients with borderline personality disorder. Neuroimage Clin 2019;24:102032. DOI: 10.1016/j.nicl.2019.102032
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.