Priapism is a rare pathological condition in which a penis remains erect for an hour in the absence of stimulation or after stimulation has ended. Priapism can be of ischemic, nonischemic, and recurrent ischemic types. Ischemic type is also known as low-flow and likewise nonischemic as high-flow as well as recurrent ischemic as intermittent. Causes for ischemic priapism are many. Medications like antipsychotics are also responsible. α-adrenergic blockage is related to antipsychotics-associated priapism. The α-receptors mediate this that are located in the corpora cavernosa of the penis. A patient with risperidone-induced priapism is reported here. Switching to olanzapine resolved his problem. A drug which has α-1-blocking properties that are less marked is a preferred choice for switch. Unfortunately, we are yet to reach a consensus regarding what is the best choice of medication. It is pertinent to search for priapism risk factors. Thereafter, one should proceed to antipsychotic prescription. Not only the patient should know about this adverse effect but also one should know the need for urgent medical intervention.
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