Paediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) is a unique syndrome which is associated with a recent infection caused by the group A b-haemolytic streptococcal bacteria. Although b-haemolytic streptococcal infection is prevalent in India, we are less aware of cases of PANDAS from the Indian subcontinent. We report a case of OCD who presented to us with features of PANDAS.
Swedo S, Leonard HL, Garvey M, et al. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection: clinical descriptions of the first50cases. Am J Psychiatry. 1998;155:264-271.
National Institute of Mental Health. Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). http://intramural.nimh.nih.gov/pdn/web.htm.
Nandi S, Kumar R, Ray P, Vohra H, Ganguly NK. Group A Streptococcal Sore Throat In A Periurban Population Of Northern India: A One-Year Prospective Study. Bull World Health Organ 2001, 79:528–33.
Murphy T. Tics, compulsions and strep throat. Program and abstracts of the American Academy of Child and Adolescent Psychiatry 49th Annual Meeting; October 22-27, 2002; San Francisco, California. Institute.
Riddle M, Reeve EA, Yaryura-Tobias JA, et al. Fluvoxamine for children and adolescents with obsessivecompulsive disorder; a randomized, controlled, multicenter trial. J Am Acad Child Adolesc Psychiatry. 2001;40:222-229.
Garvey MA, Perlmutter SJ, Allen AJ, et al. A pilot study of penicillin prophylaxis for neuropsychiatic exacerbations triggered by streptococcal infections. Biol Psychiatry. 1999;45:1564-1571.
Swedo S. Pediatric autoimmune neuropsychiatric disorders associated with strep infections (PANDAS). Program and abstracts of the American Academy of Child and Adolescent Psychiatry 49th Annual Meeting; October 22-27, 2002; San Francisco, California. Symposium.
Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL, et al. Therapeutic plasma exchange and intravenous immunoglobulin for obsessive–compulsive disorder and tic disorders in childhood. Lancet 1999;354:1153–8.
Bodner SM, Morshed SA, Peterson BS. The question of PANDAS in adults. Biological Psychiatry, 2001; 49:807–810.
Murphy ML, Pichichero ME. Prospective identification and treatment of children with paediatric autoimmune neuropsychiatric disorder associated with Group A streptococcal infection (PANDAS). Arch Pediatr Adolesc Med 2002;156: 356-61
