Eastern Journal of Psychiatry

Register      Login

VOLUME 13 , ISSUE 1-2 ( February-August, 2010 ) > List of Articles

Original Article

A Comparative Study of Neurocognitive Impairment in Elderly Patients with Schizophrenia and Elderly Normals

Nawab Akhtar Khan, Amrita Kanchan, Archana Singh, K.S. Sengar, A.K. Nag

Keywords : Cognitive assessment, Cognitive Impairment, Schizophrenia

Citation Information : Khan NA, Kanchan A, Singh A, Sengar K, Nag A. A Comparative Study of Neurocognitive Impairment in Elderly Patients with Schizophrenia and Elderly Normals. 2010; 13 (1-2):60-64.

DOI: 10.5005/EJP-13-1--2-60

License: CC BY-NC 4.0

Published Online: 13-10-2021

Copyright Statement:  Copyright © 2010; The Author(s).


Abstract

Background: Cognitive impairment has been known to be a feature of Schizophrenia since the illness was first described in a systematic manner. The course of cognition and functional status in schizophrenia remains an area of significant controversy and is marked by conflicting findings. One of the reasons for this controversy is that cognitive and functional changes occur with normal aging in the population. Method: Total number of samples in the study were 80 (experimental and control), out of which 40 were elderly schizophrenic patients and 40 were normal elderly individuals. Elderly patients with schizophrenia were selected from the inpatient department of RINPAS, Ranchi. Normal elderly people were selected from near by areas of the hospital. On both the groups the Post Graduate Institute- Battery for Assessment of Mental Efficiency in Elderly (PGI- AMEE) test was administered. Result: Significant differences were found in mental efficiency between normal elderly group and elderly schizophrenic patients. The mean score of normal population is 52.90 and for schizophrenic group 40.20. Conclusion: The findings of the index study suggests that the marked differences in cognitive functioning has been found between elderly patient with schizophrenia and normal elderly people. Areas of impairment were difficulty in recalling names of different things, general orientation and visuo-spatial coordination.


PDF Share
  1. Gold, J.M. & Harvey, P.D. (1993) Cognitive deficits in schizophrenia; Psychiatric. Clinic of North America; 16, 295 312.
  2. Davidson, M. Harvey, P.D., & Powchik, P. (1995) Severity of symptoms in geriatric chronic schizophrenic inpatients; Am. J. Psychiatry; 152, 197–207.
  3. Perlick, D., Mattis, S., & Statsny, P. (1992) Neuropsychological discriminators of long-term inpatient or outpatient status in chronic schizophrenia; J. Neuropsychiatry Clin. Neurosci; 4, 428-434.
  4. Wyatt, R.J. & Hanter, I.D. (1998) The effects of early and sustained intervention on the long term morbidity on schizophrenia.; J Psychiatr Res; 32: 169-177.
  5. Jaeger, J., & Douglas, E. (1992) Neuropsychiatric rehabilitation for persistent mental illness; Psychiat. Quart; 63, 71–93.
  6. Meltzer, H.Y. & McGurk, S.R. (1999) The effects of clozapine risperidone and olanzapine on cognitive functioning in schizophrenia; Schizophrenia. Bulletin., in press.
  7. Harvey, P.D., Howanitz, E., Parrella, M., White, L., Hoblyn, J., Mohs, R.C. & Davis, K.L., (1998) Cognitive adaptive and clinical symptoms in geriatric patients with lifelong schizophrenia: A comparative study across treatment sites; Am. J. Psychiatry; 155, 1080–1086 Brink, T. L., Yesavage, J. A., Lum, O., Heersema, P. H., Adey, M., (1982) Screening tests for geriatric depression; Clinical Gerontologist, 1, 37-43.
  8. Harvey, P.D., Sukhodolsky, D., Parrella, M., White, L. & Davidson, M. (1997c) The association between adaptive and cognitive deficits in geriatric chronic schizophrenic patients; Schizophrenia Research; 27, 211–218.
  9. Velligan, D.I., Mahurin, R.K., Diamond, P.L., Hazleton, B.C., Eckert, S.L. & Miller, A.L., (1997) The functional significance of symptomotology and cognitive function in schizophrenia; Schizophrenia Research; 25, 21–31.
  10. Mueser, K.T., Bellack, A.S., Douglas, M.S., & Wade, J.H. (1991) Prediction of social skills acquisition in schizophrenic and major affective disorder patients from memory and symptomotology; Psychiatric Research; 37, 281–296.
  11. Corrigan, P.W., Wallace, C.J., Schade, M.I., Green, M.F., (1994) Cognitive dysfunctions and psychosocial skill learning in schizophrenia; Behaviour Therapy; 25, 5–15.
  12. Lysaker, P., Bell, M. & Beam-Goulet, J. (1995) Wisconsin Card Sorting Test and work performance in schizophrenia; Psychiatric Research; 56, 45–51.
  13. Harvey, P.D., Lombardi, J., Leibman, M., White, L., Parrella, M., Powchik, P. & Davidson, M. (1996) Cognitive impairment and negative symptoms in schizophrenia: A prospective study of their relationship; Schizophrenia Research; 22, 223–231.
  14. Harvey, P.D., Parrella, M., White, L., Mohs, R.C. & Davis, K.L. (1999a) The convergence of cognitive and adaptive decline in late-life schizophrenia; Schizophrenia Research., in press.
  15. Goldberg, D. & Williams, P. (1988) Manual of the General Health Questionnaire. winder; NFER-Nelson Park, D. C. (1992) Applied cognitive aging research; Pp 449-93.
  16. Kay, S.R., Opler., L.A., Lindenmayer., J.P. (1987) The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia; Schizophrenia bulletin; 13, 261-276
  17. Park, D. C. (1992) Applied cognitive aging research; Pp 449-93.
  18. Craik, In., Fergus I. M. & Salthouse, T. A. (1992) The Handbook of Aging and Cognition; Hillsdale, NJ: LEA; Pp 111-165.
  19. Starr, J.M., Deary, I.J., Inch, S., Cross, S. & MacLennan, W.J. (1997) Age-associated cognitive decline in healthy old people; Age and Ageing.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.